An Efficient Catalyst for Pd-Catalyzed Carbonylation of Aryl Arenesulfonates

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• 作者：Chaoxian Cai ; Nelo R. Rivera ; Jaume Balsells ; Rick R. Sidler ; J. Christopher McWilliams ; C. Scott Shultz ; Yongkui Sun
• 刊名：Organic Letters
• 出版年：2006
• 出版时间：October 26, 2006
• 年：2006
• 卷：8
• 期：22
• 页码：5161 - 5164
• 全文大小：135K
• 年卷期：v.8,no.22(October 26, 2006)
• ISSN：1523-7052

文摘

Aryl carboxylic esters were synthesized by Pd-catalyzed carbonylation of aryl p-fluorobenzenesulfonates or -tosylates. A unique Josiphosligand was discovered through high-throughput catalyst screening, which was the key for the successful carbonylation of various substrates.This catalyst is effective and works well for both electron-rich and electron-poor aryl arenesulfonates. Isolated yields of up to 90% wereobtained for aryl p-fluorobenzenesulfonates and -tosylates.