Free-Standing Biomimetic Polymer Membrane Imaged with Atomic Force Microscopy

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• 作者：Christian Rein ; Kamila Pszon-Bartosz ; Karin B. Stibius ; Thomas Bj酶rnholm ; Claus He虂lix-Nielsen
• 刊名：Langmuir
• 出版年：2011
• 出版时间：January 18, 2011
• 年：2011
• 卷：27
• 期：2
• 页码：499-503
• 全文大小：825K
• 年卷期：v.27,no.2(January 18, 2011)
• ISSN：1520-5827

文摘

Fluid polymeric biomimetic membranes are probed with atomic force microscopy (AFM) using probes with both normal tetrahedrally shaped tips and nanoneedle-shaped Ag₂Ga rods. When using nanoneedle probes, the collected force volume data show three distinct membrane regions which match the expected membrane structure when spanning an aperture in a hydrophobic scaffold. The method used provides a general method for mapping attractive fluid surfaces. In particular, the nanoneedle probing allows for characterization of free-standing biomimetic membranes with thickness on the nanometer scale suspended over 300-渭m-wide apertures, where the membranes are stable toward hundreds of nanoindentations without breakage.