The Xanthophyll Composition of Biofortified Maize (Zea mays Sp.) Does Not Influence the Bioefficacy of Provitamin A Carotenoids in Mongolian Gerbils (Meriones unguiculatus)
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- 作者：Christopher R. Davis ; Julie A. Howe ; Torbert R. Rocheford ; Sherry A. Tanumihardjo
- 刊名：Journal of Agricultural and Food Chemistry
- 出版年：2008
- 出版时间：August 13, 2008
- 年：2008
- 卷：56
- 期：15
- 页码：6745-6750
- 全文大小：164K
- 年卷期：v.56,no.15(August 13, 2008)
- ISSN：1520-5118
文摘
Maize has been targeted for biofortification with provitamin A carotenoids through traditional breeding. Two studies were conducted in gerbils to evaluate factors that may affect provitamin A activity. Maize diets had equal theoretical concentrations of vitamin A (VA) assuming 100% bioefficacy. Study 1 (n = 57) varied the ratio of β-cryptoxanthin and β-carotene but maintained the same theoretical VA. Study 2 (n = 67) varied lutein and zeaxanthin. Other treatments were oil, VA, or β-carotene doses. Serum and livers were analyzed for VA and carotenoids. In study 1, total liver VA did not differ among the maize groups. In study 2, total liver VA of the VA and maize groups were higher than controls (P < 0.05). Conversion factors were 2.1−3.3 μg β-carotene equivalents to 1 μg retinol. Twice the molar amount of β-cryptoxanthin was as efficacious as β-carotene and the proportion of β-cryptoxanthin or xanthophylls did not appreciably change the VA value of biofortified maize.