Marsupellins A鈥揊, ent-Longipinane-Type Sesquiterpenoids from the Chinese Liverwort Marsupella alpine with Acetylcholinesterase Inhibitory Activity
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- 作者：Jiaozhen Zhang ; Peihong Fan ; Rongxiu Zhu ; Ruijuan Li ; Zhaomin Lin ; Bin Sun ; Chunmei Zhang ; Jinchuan Zhou ; Hongxiang Lou
- 刊名：Journal of Natural Products
- 出版年：2014
- 出版时间：April 25, 2014
- 年：2014
- 卷：77
- 期：4
- 页码：1031-1036
- 全文大小：324K
- 年卷期：v.77,no.4(April 25, 2014)
- ISSN：1520-6025
文摘
Acetylcholinesterase (AChE) inhibitory activity-guided fractionation of the Chinese liverwort Marsupella alpine afforded six new [marsupellins A鈥揊 (1鈥?b>6)] and three known (7鈥?b>9) ent-longipinane-type sesquiterpenoids. The structures were determined from MS and NMR spectroscopic data, single-crystal X-ray diffraction, and electronic circular dichroism calculations. Compounds 1鈥?b>9 exhibited moderate to weak AChE inhibitory activity.