Rumen-bypass microcapsules were prepared by a spray-dry method for protection against microbialhydrogenation in the
rumen (neutral
pH). Porous starch was used as the core material, and themicrocapsules were prepared by a triple coating of Eudragit E100, AS-HF, and shellac. Capsuleswere generated with yield of about 48% and a mean particle diameter of 20-30
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m. Themicrocapsules had high stability in a neutral solution that mimicked a ruminal pH (pH 6.5).Moreover, when microcapsules were incubated in the presence of ruminal microorganisms, about65% of the microcapsules were resistant to digestion in ruminal fluids, and protection of the inclusionsubstance was observed. In addition, the efficiency of release of these microcapsules was about 85%within only 30 min in the abomasal environment (pH 3.0).Keywords: Microcapsule; spray-dry method;
rumen-bypass; shellac; resistance to ruminal microorganisms