Efficient Synthesis of a New Structural Phenanthro[9,10,3',4']indolizidine Starting from Pyrrole

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• 作者：Kailiang Wang ; Qingmin Wang ; Runqiu Huang
• 刊名：Journal of Organic Chemistry
• 出版年：2007
• 出版时间：October 26, 2007
• 年：2007
• 卷：72
• 期：22
• 页码：8416 - 8421
• 全文大小：164K
• 年卷期：v.72,no.22(October 26, 2007)
• ISSN：1520-6904

文摘

A new structural phenanthroindolizidine, 2,3,6,7-tetramethoxyphenanthro[9,10,3',4']indolizidine, has beensynthesized efficiently from pyrrole. An important feature of this synthesis is that intramolecular oxidativecoupling and rearrangement of 6,7-bis(3,4-dimethoxyphenyl)-8-methoxy-1,2,3-trihydroindolizin-5-one byusing VOF₃ and TFA have been achieved in one pot.