Synthetic Studies on Polymaxenolides: Synthesis and Structure Elucidation of Nominal Epoxyafricanane and Other Africane-Type Sesquiterpenoids
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- 作者：Yutaka Matsuda ; Yusuke Endo ; Yoko Saikawa ; Masaya Nakata
- 刊名：Journal of Organic Chemistry
- 出版年：2011
- 出版时间：August 5, 2011
- 年：2011
- 卷：76
- 期：15
- 页码：6258-6263
- 全文大小：867K
- 年卷期：v.76,no.15(August 5, 2011)
- ISSN：1520-6904
文摘
A racemic total synthesis of the sesquiterpenoid unit of the hybrid marine natural product polymaxenolide has been achieved based on a three-component assembly followed by ring-closing metathesis as the key steps. However, the spectral data of our product synthesized from 螖9(15)-africanene by epoxidation were not identical with those of the natural product named epoxyafricanane. The structure confirmation of the synthetic nominal epoxyafricanane is described.