Synthesis of 2,3-Dihydroquinolin-4(1H)-ones through Catalytic Metathesis of o-Alkynylanilines and Aldehydes

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• 作者：Akio Saito ; Jun Kasai ; Yu Odaira ; Haruhiko Fukaya ; Yuji Hanzawa
• 刊名：Journal of Organic Chemistry
• 出版年：2009
• 出版时间：August 7, 2009
• 年：2009
• 卷：74
• 期：15
• 页码：5644-5647
• 全文大小：726K
• 年卷期：v.74,no.15(August 7, 2009)
• ISSN：1520-6904

文摘

SbF₅−MeOH catalytic system efficiently promotes the alkyne−carbonyl metathesis of o-alkynylaniline derivatives and aldehydes to afford 2,3-disubstituted dihydroquinolinones in moderate to high yields with high trans-selectivity.