Synthesis of Tricyclic Benzazocines by Aza-Prins Reaction

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• 作者：Tomohiro Katamura ; Tomoaki Shimizu ; Yuichiro MutohShinichi Saito
• 刊名：Organic Letters
• 出版年：2017
• 出版时间：January 6, 2017
• 年：2017
• 卷：19
• 期：1
• 页码：266-269
• 全文大小：349K
• ISSN：1523-7052

文摘

The aza-Prins reaction of 3-vinyltetrahydroquinolines with aldehydes proceeded smoothly in the presence of hydrogen halides, and the tricyclic benzazocine derivatives were isolated in good to high yields. The reaction would proceed through the formation and cyclization of the iminium ion intermediate.