Protoaculeine B, a Putative N-Terminal Residue for the Novel Peptide Toxin Aculeines

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• 作者：Satoko Matsunaga ; Reimi Kishi ; Kazunori Otsuka ; Masaki J Fujita ; Masato Oikawa ; Ryuichi Sakai
• 刊名：Organic Letters
• 出版年：2014
• 出版时间：June 6, 2014
• 年：2014
• 卷：16
• 期：11
• 页码：3090-3093
• 全文大小：244K
• 年卷期：v.16,no.11(June 6, 2014)
• ISSN：1523-7052

文摘

A new polyamine-modified indole derivative protoaculeine B (1) was isolated from Okinawan marine sponge Axinyssa aculeata. The structure of 1 was assigned on the basis of spectral data along with chemical transformations. Because the structure of 1 greatly inferred the N-terminal amino acid for highly modified peptide toxin aculeines, the probable structure for aculeine B was proposed on the basis of high-resolution mass spectral analysis.