Recognition of Hg2+ Using Diametrically Disubstituted Cyclam Unit

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• 作者：Prasenjit Mahato ; Amrita Ghosh ; Sukdeb Saha ; Sandhya Mishra ; Sanjiv K. Mishra ; Amitava Das
• 刊名：Inorganic Chemistry
• 出版年：2010
• 出版时间：December 20, 2010
• 年：2010
• 卷：49
• 期：24
• 页码：11485-11492
• 全文大小：987K
• 年卷期：v.49,no.24(December 20, 2010)
• ISSN：1520-510X

文摘

A newly synthesized 1,4,8,11-tetraazacyclotetradecane derivative (L), functionalized with a diazo moiety as the reporter functionality, is found to bind specifically to Hg²⁺ with an associated change in color that could be visually detected. With biologically benign β-CD, it forms an inclusion complex (L·2β-CD), which shows a much higher solubility in water, and this helps in developing a more intense color on binding to Hg²⁺ in a CH₃CN-HEPES buffer medium. The nontoxic nature of L was checked with the living cells of a Gram negative bacterium, Pseudomonas putida. Further, experiments revealed that these two reagents could be used as staining agents for the detection of Hg²⁺ present in this microorganism.