(DHQ)2AQN-Catalyzed Asymmetric Substitution of Isatin-Derived Hydrazones with O-Boc-Protected Morita鈥揃aylis鈥揌illman Adducts: A Strategy for Synthesizing Enantioenriched Azo Compounds Incorp
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- 作者：Hai-Bin Yang ; Yun-Zhou Zhao ; Rui Sang ; Min Shi
- 刊名：Journal of Organic Chemistry
- 出版年：2014
- 出版时间：April 18, 2014
- 年：2014
- 卷：79
- 期：8
- 页码：3519-3528
- 全文大小：381K
- 年卷期：v.79,no.8(April 18, 2014)
- ISSN：1520-6904
文摘
The first example for the preparation of enantioenriched azo compounds from hydrazones and Morita鈥揃aylis鈥揌illman adducts has been developed, affording azo compounds incorporating an oxindole scaffold in up to 91% yield along with a 93% ee value under the catalysis of (DHQ)2AQN.