Copper(II)−Bis(oxazoline) Catalyzed Asymmetric Diels−Alder Reaction with α′-Arylsulfonyl Enones as Dienophiles

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• 作者：Santiago Barroso ; Gonzalo Blay ; Lina Al-Midfa ; M. Carmen Muñ ; oz ; José ; R. Pedro
• 刊名：Journal of Organic Chemistry
• 出版年：2008
• 出版时间：August 15, 2008
• 年：2008
• 卷：73
• 期：16
• 页码：6389-6392
• 全文大小：203K
• 年卷期：v.73,no.16(August 15, 2008)
• ISSN：1520-6904

文摘

α′-Arylsulfonyl enones are efficient bidentate dienophiles for the Cu(II)-bis(oxazoline) catalyzed enantioselective Diels−Alder reaction with a number of dienes, affording the corresponding products with good to high enantiomeric excesses. The resulting products can be alkylated and the sulfone removed, so α′-arylsulfonyl enones can be regarded as surrogates of simple monodentate enones, which are poor dienophiles with this catalytic system.