Synthetic Route to Chiral Tetrahydroquinoxalines via Ring-Opening of Activated Aziridines
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- 作者：Manas K. Ghorai ; Ashis K. Sahoo ; Sarvesh Kumar
- 刊名：Organic Letters
- 出版年：2011
- 出版时间：November 18, 2011
- 年：2011
- 卷：13
- 期：22
- 页码：5972-5975
- 全文大小：807K
- 年卷期：v.13,no.22(November 18, 2011)
- ISSN：1523-7052
文摘
A highly regio- and stereoselective route for the synthesis of racemic and nonracemic tetrahydroquinoxalines via the SN2-type ring-opening of activated aziridines with 2-bromoanilines followed by the Pd-catalyzed intramolecular C鈥?/b>N bond formation is described.