Ligand-Controlled, Tunable Silver-Catalyzed C鈥揌 Amination
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- 作者：Juliet M. Alderson ; Alicia M. Phelps ; Ryan J. Scamp ; Nicholas S. Dolan ; Jennifer M. Schomaker
- 刊名：Journal of the American Chemical Society
- 出版年：2014
- 出版时间：December 3, 2014
- 年：2014
- 卷：136
- 期：48
- 页码：16720-16723
- 全文大小：461K
- ISSN：1520-5126
文摘
The development of readily tunable and regioselective C鈥揌 functionalization reactions that operate solely through catalyst control remains a challenge in modern organic synthesis. Herein, we report that simple silver catalysts supported by common nitrogenated ligands can be used to tune a nitrene transfer reaction between two different types of C鈥揌 bonds. The results reported herein represent the first example of ligand-controlled and site-selective silver-promoted C鈥揌 amination.