Switching the Z/E Selectivity in the Palladium(II)-Catalyzed Decarboxylative Heck Arylations of trans-Cinnamaldehydes by Solvent

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• 作者：Shu-Rong Ban ; Hai-Ning Wang ; Violeta Toader ; D. Scott Bohle ; Chao-Jun Li
• 刊名：Organic Letters
• 出版年：2014
• 出版时间：December 19, 2014
• 年：2014
• 卷：16
• 期：24
• 页码：6282-6285
• 全文大小：308K
• ISSN：1523-7052

文摘

The Z/E selectivity of Pd(II)-catalyzed decarboxylative Heck-type arylations of trans-cinnamaldehydes can be controlled readily by switching the reaction solvent. Depending on the type of solvent used, each of the two isomeric products can be obtained with good to excellent Z/E ratio. In THF, Z-isomers were formed preferentially, whereas DMF provided the E-isomers predominantly.