Solid-Supported Cross Metathesis and the Role of the Homodimerization of the Non-immobilized Olefin

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• 作者：André ; s A. Poeylaut-Palena ; Sebasti&aacute ; n A. Testero ; Ernesto G. Mata
• 刊名：Journal of Organic Chemistry
• 出版年：2008
• 出版时间：March 7, 2008
• 年：2008
• 卷：73
• 期：5
• 页码：2024 - 2027
• 全文大小：121K
• 年卷期：v.73,no.5(March 7, 2008)
• ISSN：1520-6904

文摘

We have prepared immobilized olefins as models for thecross metathesis using different olefin partners in thepresence of second generation Grubbs and Hoveyda-Grubbsprecatalysts. We have demonstrated that solid-phase crossmetathesis is strongly dependent on the degree of homodimerization of the non-immobilized olefin and the reactivityof such a homodimer. As in the homogeneous phase, theHoveyda-Grubbs precatalyst was better for immobilized,-unsaturated carbonyl compounds.