Shining Light on the Dark Side of Imaging: Excited State Absorption Enhancement of a Bis-styryl BODIPY Photoacoustic Contrast Agent

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• 作者：Mathieu Frenette ; Maryam Hatamimoslehabadi ; Stephanie Bellinger-Buckley ; Samir Laoui ; Jeffrey La ; Seema Bag ; Srivalleesha Mallidi ; Tayyaba Hasan ; Brett Bouma ; Chandra Yelleswarapu ; Jonathan Rochford
• 刊名：Journal of the American Chemical Society
• 出版年：2014
• 出版时间：November 12, 2014
• 年：2014
• 卷：136
• 期：45
• 页码：15853-15856
• 全文大小：265K
• ISSN：1520-5126

文摘

A first approach toward understanding the targeted design of molecular photoacoustic contrast agents (MPACs) is presented. Optical and photoacoustic Z-scan spectroscopy was used to identify how nonlinear (excited-state) absorption contributes to enhancing the photoacoustic emission of the curcuminBF₂ and bis-styryl (MeOPh)₂BODIPY dyes relative to Cy3.