Fluoroalkylcopper(I) Complexes Generated by the Carbocupration of Tetrafluoroethylene: Construction of a Tetrafluoroethylene-Bridging Structure

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• 作者：Hiroki Saijo ; Masato Ohashi ; Sensuke Ogoshi
• 刊名：Journal of the American Chemical Society
• 出版年：2014
• 出版时间：October 29, 2014
• 年：2014
• 卷：136
• 期：43
• 页码：15158-15161
• 全文大小：326K
• ISSN：1520-5126

文摘

We report a copper-mediated synthesis of a variety of 1,2-difunctionalized-1,1,2,2-tetrafluoroethylene derivatives via the carbocupration of tetrafluoroethylene. The key synthetic intermediates, 2-aryl-1,1,2,2-tetrafluoroethylcopper complexes, can be easily prepared, stored, and used as fluoroalkylation reagents. The molecular structure was unambiguously determined by X-ray crystallography and NMR analysis. We applied this method to the short-step synthesis of a liquid-crystalline compound bearing a tetrafluoroethylene-bridging structure.