Alkenylation of Phosphacoumarins via Aerobic Oxidative Heck Reactions and Their Synthetic Application to Fluorescent Benzophosphacoumarins
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- 作者：Cheol-Eui Kim ; Jeong-Yu Son ; Seohyun Shin ; Boram Seo ; Phil Ho Lee
- 刊名：Organic Letters
- 出版年：2015
- 出版时间：February 20, 2015
- 年：2015
- 卷：17
- 期：4
- 页码：908-911
- 全文大小：349K
- ISSN：1523-7052
文摘
Alkenylation of phosphacoumarins is developed from the reaction of phosphacoumarins with a variety of activated as well as nonactivated alkenes via aerobic oxidative Heck reactions. In addition, 3-alkenylphosphacoumarins undergo an inverse electron demand Diels鈥揂lder reaction (IEDDA) with enamines in situ generated from ketone and pyrrolidine followed by 1,2-elimination and a dehydrogenation, producing fluorescent benzophosphacoumarins.