Stereoselective Palladium-Catalyzed 伪-Arylation of 3-Aryl-1-Indanones: An Asymmetric Synthesis of (+)-Pauciflorol F

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• 作者：Bong Hyang Lee ; Young Lok Choi ; Seunghoon Shin ; Jung-Nyoung Heo
• 刊名：Journal of Organic Chemistry
• 出版年：2011
• 出版时间：August 19, 2011
• 年：2011
• 卷：76
• 期：16
• 页码：6611-6618
• 全文大小：1002K
• 年卷期：v.76,no.16(August 19, 2011)
• ISSN：1520-6904

文摘

Highly stereoselective, palladium-catalyzed 伪-arylation reactions of 3-aryl-1-indanones with aryl bromides are described. The use of sodium tert-butoxide as a base in this process is required to elevate the efficiencies and stereoselectivities of these reactions. The new methodology was successfully applied to a highly efficient route for the asymmetric synthesis of (+)-pauciflorol F.