Entry to 尾-Alkoxyacrylates via Gold-Catalyzed Intermolecular Coupling of Alkynoates and Allylic Ethers
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- 作者：Sae Rom Park ; Cheoljae Kim ; Dong-gil Kim ; Neetipalli Thrimurtulu ; Hyun-Suk Yeom ; Jungho Jun ; Seunghoon Shin ; Young Ho Rhee
- 刊名：Organic Letters
- 出版年：2013
- 出版时间：March 15, 2013
- 年：2013
- 卷：15
- 期：6
- 页码：1166-1169
- 全文大小：262K
- 年卷期：v.15,no.6(March 15, 2013)
- ISSN：1523-7052
文摘
The first gold-catalyzed intermolecular coupling of alkynoates and allylic ethers invoking alkoxy addition and [3,3]-sigmatropic rearrangement as the key mechanism has been developed. Remarkably, the reaction showed complete chemoselectivity toward the pathway initiated by the alkoxy addition to alkynes. This unprecedented reactivity led to a new access to diversely substituted 尾-alkoxyacrylates in a highly efficient manner.