Selectfluor-Mediated Simultaneous Cleavage of C鈥揙 and C鈥揅 Bonds in 伪,尾-Epoxy Ketones Under Transition-Metal-Free Conditions: A Route to 1,2-Diketones

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• 作者：Heng Wang ; Shaobo Ren ; Jian Zhang ; Wei Zhang ; Yunkui Liu
• 刊名：Journal of Organic Chemistry
• 出版年：2015
• 出版时间：July 2, 2015
• 年：2015
• 卷：80
• 期：13
• 页码：6856-6863
• 全文大小：477K
• ISSN：1520-6904

文摘

Selectfluor-mediated simultaneous cleavage of C鈥揙 and C鈥揅 bonds in 伪,尾-epoxy ketones has been successfully achieved under transition-metal-free conditions. The reaction gives 1,2-diketone compounds in moderate to good yields involving a ring-opening/benzoyl rearrangement/C鈥揅 bond cleavage sequence under oxidative conditions.