Copper-Catalyzed Electrophilic Amination of Organoaluminum Nucleophiles with O-Benzoyl Hydroxylamines

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• 作者：Shuangliu Zhou ; Zhiyong Yang ; Xu Chen ; Yimei Li ; Lijun Zhang ; Hong Fang ; Wei Wang ; Xiancui Zhu ; Shaowu Wang
• 刊名：Journal of Organic Chemistry
• 出版年：2015
• 出版时间：June 19, 2015
• 年：2015
• 卷：80
• 期：12
• 页码：6323-6328
• 全文大小：400K
• ISSN：1520-6904

文摘

A copper-catalyzed electrophilic amination of aryl and heteroaryl aluminums with N,N-dialkyl-O-benzoyl hydroxylamines that affords the corresponding anilines in good yields has been developed. The catalytic reaction proceeds very smoothly under mild conditions and exhibits good substrate scope. Moreover, the developed catalytic system is also well suited for heteroaryl aluminum nucleophiles, providing facile access to heteroaryl amines.