Pulsed Dynamic Nuclear Polarization with Trityl Radicals
详细信息 查看全文
- 作者：Guinevere Mathies ; Sheetal Jain ; Marcel Reese ; Robert G. Griffin
- 刊名：The Journal of Physical Chemistry Letters
- 出版年：2016
- 出版时间：January 7, 2016
- 年：2016
- 卷：7
- 期：1
- 页码：111-116
- 全文大小：328K
- ISSN：1948-7185
文摘
Continuous-wave (CW) dynamic nuclear polarization (DNP) is now established as a method of choice to enhance the sensitivity in a variety of NMR experiments. Nevertheless, there remains a need for the development of more efficient methods to transfer polarization from electrons to nuclei. Of particular interest are pulsed DNP methods because they enable a rapid and efficient polarization transfer that, in contrast with CW DNP methods, is not attenuated at high magnetic fields. Here we report nuclear spin orientation via electron spin-locking (NOVEL) experiments using the polarizing agent trityl OX063 in glycerol/water at a temperature of 80 K and a magnetic field of 0.34 T. 1H NMR signal enhancements up to 430 are observed, and the buildup of the local polarization occurs in a few hundred nanoseconds. Thus, NOVEL can efficiently dynamically polarize 1H atoms in a system that is of general interest to the solid-state DNP NMR community. This is a first, important step toward the general application of pulsed DNP at higher fields.