Convenient Synthesis of Triphenylphosphanylidene Spiro[cyclopentane-1,3鈥?indolines] and Spiro[cyclopent[2]ene-1,3鈥?indolines] via Three-Component Reactions
文摘
Three-component reactions of triphenylphosphine, but-2-ynedioate, and isatylidene malononitrile (ethyl cyanoacetate) in dimethoxyethane resulted in triphenylphosphanylidene spiro[cyclopentane-1,3鈥?indolines] in satisfactory yields. Furthermore, similar three-component reactions of triphenylphosphine, hex-2-en-4-ynedioate, and isatylidene malononitrile (ethyl cyanoacetate) afforded functionalized spiro[cyclopent[2]ene-1,3鈥?indolines] in good yields.