Aerobic Oxidative Cycloaddition of 伪-Chlorotosylhydrazones with Arylamines: General Chemoselective Construction of 1,4-Disubstituted and 1,5-Disubstituted 1,2,3-Triazoles under Metal-Free and Azide-Fr
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- 作者：Hui-Wen Bai ; Zhong-Jian Cai ; Shun-Yi Wang ; Shun-Jun Ji
- 刊名：Organic Letters
- 出版年：2015
- 出版时间：June 19, 2015
- 年：2015
- 卷：17
- 期：12
- 页码：2898-2901
- 全文大小：321K
- ISSN：1523-7052
文摘
A novel synthetic approach toward 1,4-disubstituted 1,2,3-triazoles and 1,5-disubstituted 1,2,3-triazoles by aerobic oxidative cycloaddition of 伪-chlorotosylhydrazone with primary aryl amine has been developed. Significantly, the reaction proceeds smoothly to afford 1,4-disubstituted 1,2,3-triazoles and 1,5-disubstituted 1,2,3-triazoles under catalyst-free, metal-free, azide-free, and peroxide-free conditions.