Synthesis of 2,3-Dihydrothieno(2,3-b)quinolines and Thieno(2,3-b)- quinolines via an Unexpected Domino Aza-MBH/Alkylation/Aldol Reaction

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• 作者：Pei-Shun Wei ; Meng-Xue Wang ; Dong-Cheng Xu ; Jian-Wu Xie
• 刊名：Journal of Organic Chemistry
• 出版年：2016
• 出版时间：February 5, 2016
• 年：2016
• 卷：81
• 期：3
• 页码：1216-1222
• 全文大小：402K
• ISSN：1520-6904

文摘

An efficient, mild, and convenient method for the preparation of 2,3-dihydrothieno(2,3-b)quinolines and thieno(2,3-b)-quinolines via an unexpected domino aza-Morita–Baylis–Hillman/alkylation/aldol reaction has been developed. The plausible mechanisms for the unexpected reaction are also given.