Phenolic Antioxidants from the Heartwood of Acacia confusa
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- 作者：Jyh-Horng Wu ; Yu-Tang Tung ; Sheng-Yang Wang ; Lie-Fen Shyur ; Yueh-Hsiung Kuo ; and Shang-Tzen Chang
- 刊名：Journal of Agricultural and Food Chemistry
- 出版年：2005
- 出版时间：July 27, 2005
- 年：2005
- 卷：53
- 期：15
- 页码：5917 - 5921
- 全文大小：97K
- 年卷期：v.53,no.15(July 27, 2005)
- ISSN：1520-5118
文摘
In the present study, the ethanolic extracts from the heartwood of Acacia confusa, a species indigenousto Taiwan, exhibit strong antioxidant effects. Among all the fractions from ethanolic extracts ofheartwood, the EtOAc soluble fraction exhibits the best antioxidant activity. The 80% 1,1-diphenyl-2-picrylhydrazyl radical inhibitory activity by the EtOAc extract was observed at a concentration of 5
g/mL, and at the same dosage there was a similar free radical scavenging activity for (-)-ascorbicacid and (+)-catechin, both of which are well-known antioxidants. In addition, the EtOAc extract alsoprotects 
X174 supercoiled DNA against strand scission induced by hydroxyl radical. Furthermore,following by column chromatography and reverse-phase high-performance liquid chromatorgrapy,10 pure phenolic compounds, including three major antioxidants (3,7,8,3',4'-pentahydroxyflavone,7,8,3',4'-tetrahydroxy-3-methoxyflavone, and 3,4,2',3',4'-pentahydroxy-trans-chalcone) and a newflavonoid (3,7,8,3'-tetrahydroxy-4'-methoxyflavone), were isolated from the ethanolic extracts of A.confusa heartwood.Keywords: Acacia confusa; antioxidant; flavonoids; free radical; phenolic compounds
g/mL, and at the same dosage there was a similar free radical scavenging activity for (-)-ascorbicacid and (+)-catechin, both of which are well-known antioxidants. In addition, the EtOAc extract alsoprotects X174 supercoiled DNA against strand scission induced by hydroxyl radical. Furthermore,following by column chromatography and reverse-phase high-performance liquid chromatorgrapy,10 pure phenolic compounds, including three major antioxidants (3,7,8,3',4'-pentahydroxyflavone,7,8,3',4'-tetrahydroxy-3-methoxyflavone, and 3,4,2',3',4'-pentahydroxy-trans-chalcone) and a newflavonoid (3,7,8,3'-tetrahydroxy-4'-methoxyflavone), were isolated from the ethanolic extracts of A.confusa heartwood.Keywords: Acacia confusa; antioxidant; flavonoids; free radical; phenolic compounds