Enantioselective Recognition for Many Different Kinds of Chiral Guests by One Chiral Receptor Based on Tetraphenylethylene Cyclohexylbisurea

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• 作者：Jia-Bin Xiong ; Wen-Zhao Xie ; Jian-Ping Sun ; Jin-Hua Wang ; Zhi-Hua Zhu ; Hai-Tao Feng ; Dong Guo ; Hui Zhang ; Yan-Song Zheng
• 刊名：Journal of Organic Chemistry
• 出版年：2016
• 出版时间：May 6, 2016
• 年：2016
• 卷：81
• 期：9
• 页码：3720-3726
• 全文大小：500K
• 年卷期：0
• ISSN：1520-6904

文摘

A neutral chiral receptor based on TPE cyclohexylbisurea was synthesized and could discriminate the enantiomers of many different kinds of chiral reagents, including chiral acidic compounds, basic compounds, amino acids, and even neutral alcohols. The ¹H NMR spectra disclosed that the ability of chiral recognition could be ascribed to the multiple hydrogen bonds and CH−π interactions between the TPE urea receptor and the enantiomer of the chiral guest, which led to the selective aggregation of the receptor with one of the two enantiomers. This result exhibited a great potential in enantiomer discernment and high-throughput analysis of enantiomer composition of these chiral analytes by one chiral AIE molecule.