Biological Imaging of HEK293 Cells Expressing PLC1 Using Surface-Enhanced Raman Microscopy
详细信息 查看全文
- 作者：Sangyeop Lee ; Sungyong Kim ; Jaebum Choo ; Soon Young Shin ; Young Han Lee ; Ha Young Choi ; Seunghan Ha ; Kyungho Kang ; Chil Hwan Oh
- 刊名：Analytical Chemistry
- 出版年：2007
- 出版时间：February 1, 2007
- 年：2007
- 卷：79
- 期：3
- 页码：916 - 922
- 全文大小：588K
- 年卷期：v.79,no.3(February 1, 2007)
- ISSN：1520-6882
文摘
Surface-enhanced Raman scattering (SERS) imaging hasbeen used for the targeting and imaging of specific cancermarkers in live cells. For this purpose, Au/Ag core-shellnanoparticles, conjugated with monoclonal antibodies,were prepared. The procedures to label live cells withthose bimetallic nanoprobes have been developed andused for highly sensitive SERS imaging of live cells. Inthe present study, live HEK293 cells expressing PLC
hars/gamma.gif" BORDER=0 >1have been used as the optical imaging target. Our resultsdemonstrate the potential feasibility of SERS imagingtechnology for the highly sensitive imaging of cancerbiomarkers in live cells.
hars/gamma.gif" BORDER=0 >1have been used as the optical imaging target. Our resultsdemonstrate the potential feasibility of SERS imagingtechnology for the highly sensitive imaging of cancerbiomarkers in live cells.