A Gel-Based Approach To Design Hierarchical CuS Decorated Reduced Graphene Oxide Nanosheets for Enhanced Peroxidase-like Activity Leading to Colorimetric Detection of Dopamine

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• 作者：Soumen Dutta ; Chaiti Ray ; Sourav Mallick ; Sougata Sarkar ; Ramkrishna Sahoo ; Yuichi Negishi ; Tarasankar Pal
• 刊名：Journal of Physical Chemistry C
• 出版年：2015
• 出版时间：October 15, 2015
• 年：2015
• 卷：119
• 期：41
• 页码：23790-23800
• 全文大小：738K
• ISSN：1932-7455

文摘

Supramolecular colorless copper(I)鈥搕hiourea hydrogel (Cu-TU gel) has been made a mechanically strong functional hybrid material in the graphene oxide (GO) framework. Mild heat treatment (85 掳C) of the hybrid material fetches black product containing hierarchical copper sulfide decorated reduced graphene oxide nanosheets (CuS-rGO) through an obvious in-house redox transformation reaction between Cu(I) and GO without any additive. The as-synthesized CuS-rGO nanocomposite exhibits impressive peroxidase-like activity where oxidation of colorless 3,3鈥?5,5鈥?tetramethylbenzidine (TMB) to blue product is observed in solution phase with H₂O₂. Systematic control experiments suggest that strong covalent interaction between CuS and rGO synergistically enhances the catalytic activity of CuS-rGO in comparison to its individual counterparts. Furthermore, an important biomolecule, dopamine, has been found to selectively inhibit, in succession, the oxidizing action of H₂O₂ for TMB oxidation reaction. Thus, dopamine-dependent successive inhibition reaction creates a one-pot reporter platform to sense dopamine down to the 0.48 渭M concentration level by UV鈥搗is spectrophotometry.