Chemical Assessment of Roots of Panax notoginseng in China: Regional and Seasonal Variations in Its Active Constituents

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• 作者：Tina T. X. Dong ; Xiu M. Cui ; Zong H. Song ; Kui J. Zhao ; Zhao N. Ji ; Chun K. Lo ; and Karl W. K. Tsim
• 刊名：Journal of Agricultural and Food Chemistry
• 出版年：2003
• 出版时间：July 30, 2003
• 年：2003
• 卷：51
• 期：16
• 页码：4617 - 4623
• 全文大小：133K
• 年卷期：v.51,no.16(July 30, 2003)
• ISSN：1520-5118

文摘

Root of Panax notoginseng (Radix Notoginseng, Sanqi) is a well-known traditional Chinese medicineand is mainly cultivated in Wenshan of Yunnan, China. The active constituents include saponin,dencichine, flavonoid, and polysaccharide; however, the levels of these components vary in differentgeographical regions of growth and also show a seasonal variation. By using high-performance liquidchromatography and spectrophotometry, the contents of notoginsenoside R₁, ginsenoside R_g1, R_b1,R_d, dencichine, flavonoid, and polysaccharide were determined and compared with Radix Notoginsengcollected from different regions of growth in China, as well as from different seasons of harvest andmarket grades. Using the contents of these active constituents as markers, the best quality of RadixNotoginseng is found in the southwestern parts of Wenshan, and the best season for the harvest isSeptember to October. In addition, the unseeded plants produced a better quality of RadixNotoginseng. The current results provide useful information for the quality control of Radix Notoginsengand its further development in establishing the good agriculture practice standard of P. notoginsengin China.Keywords: Panax notoginseng; GAP; quality control; polysaccharide; saponin; seasonal variation;Chinese medicine