Molecularly Imprinted Polymer (MIP) Film with Improved Surface Area Developed by Using Metal–Organic Framework (MOF) for Sensitive Lipocalin (NGAL) Determination

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• 作者：Zofia Iskierko ; Piyush Sindhu Sharma ; Daniel Prochowicz ; Krzysztof Fronc ; Francis D’Souza ; Diana Toczydłowska ; Filip Stefaniak ; Krzysztof Noworyta
• 刊名：ACS Applied Materials & Interfaces
• 出版年：2016
• 出版时间：August 10, 2016
• 年：2016
• 卷：8
• 期：31
• 页码：19860-19865
• 全文大小：383K
• 年卷期：0
• ISSN：1944-8252

文摘

Electropolymerizable functional and cross-linking monomers were used to prepare conducting molecularly imprinted polymer film with improved surface area with the help of a sacrificial metal–organic framework (MOF). Subsequent dissolution of the MOF layer resulted in a surface developed MIP film. This surface enlargement increased the analyte accessibility to imprinted molecular cavities. Application of the porous MIP film as a recognition unit of an extended-gate field effect transistor (EG-FET) chemosensor effectively enhanced analytical current signals of determination of recombinant human neutrophil gelatinase-associated lipocalin (NGAL)