Synthesis of Aryl(2,4,6-trimethoxyphenyl)iodonium Trifluoroacetate Salts
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- 作者：Virginie Carreras ; Alexander H. Sandtorv ; David R. Stuart
- 刊名：Journal of Organic Chemistry
- 出版年：2017
- 出版时间：January 20, 2017
- 年：2017
- 卷：82
- 期：2
- 页码：1279-1284
- 全文大小：451K
- ISSN：1520-6904
文摘
The direct synthesis of aryl(2,4,6-trimethoxyphenyl)iodonium trifluoroacetate salts from aryl iodides is described. Stoichiometric quantities of trifluoroacetic acid and trimethoxybenzene are used as the counteranion and auxiliary precursors, respectively, under oxidizing conditions. The reaction occurs at mild temperature, is broad in scope, and does not require a separate anion exchange step to install the trifluoroacetate group. The intermediacy of two distinct dicarboxy aryl-λ3-iodanes is hypothesized in the mechanism.