Bioactive Compounds from Bauhinia purpurea Possessing Antimalarial, Antimycobacterial, Antifungal, Anti-inflammatory, and Cytotoxic Activities

详细信息    查看全文

• 作者：Surat Boonphong ; Pakawan Puangsombat ; Apiwat Baramee ; Chulabhorn Mahidol ; Somsak Ruchirawat ; Prasat Kittakoop
• 刊名：Journal of Natural Products
• 出版年：2007
• 出版时间：May 2007
• 年：2007
• 卷：70
• 期：5
• 页码：795 - 801
• 全文大小：90K
• 年卷期：v.70,no.5(May 2007)
• ISSN：1520-6025

文摘

Eleven new secondary metabolites (1-11), together with two known flavanones (12 and 13) and five known bibenzyls(14-18), were isolated from the root extract of Bauhinia purpurea. New compounds include eight dihydrodibenzoxepins(1-8), a dihydrobenzofuran (9), a novel spirochromane-2,1'-hexenedione (10), and a new bibenzyl (11). Antimycobacterial,antimalarial, antifungal, cytotoxic, and anti-inflammatory activities of the isolated compounds are reported, and biosyntheticpathways of these compounds are also discussed.