Electrochemical Bubble-Based Bidirectional Microfluidic Transport
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- 作者：Hirotaka Obata ; Tomoaki Kuji ; Kenichi Kojima ; Fumihiro Sassa ; Masatoshi Yokokawa ; Kazuhiro Takekoshi ; Hiroaki Suzuki
- 刊名：ACS Sensor
- 出版年：2016
- 出版时间：February 26, 2016
- 年：2016
- 卷：1
- 期：2
- 页码：190-196
- 全文大小：577K
- ISSN：2379-3694
文摘
With the aim of application to biochemical analyses, efficient bidirectional microfluidic transport was achieved through the reversible electrochemical production and shrinkage of hydrogen bubbles. A three-electrode system with a platinum black working electrode, a Ag/AgCl reference electrode, and a platinum auxiliary electrode was incorporated into a poly(dimethylsiloxane) structure containing the necessary flow channels and compartments. The influence of the electrode and flow channel structures on the operation of the system was investigated. The production and shrinkage of bubbles was achieved by applying appropriate potentials to the working electrode, which minimized the influence of spontaneous shrinkage resulting from the oxidizing effect of dissolved oxygen. Device performance depended on the structure of the working electrode, meaning that further optimization will be necessary. The device was shown to withdraw solution through a minimally invasive needle and to process liquid plugs in a microfluidic system.