Pachyelasides A-D, Novel Molluscicidal Triterpene Saponins from Pachyelasma Tessmannii
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- 作者：Ken-ichi Nihei ; Bai-ping Ying ; Takanori Murakami ; Hiroko Matsuda ; Masaru Hashimoto ; and Isao Kubo
- 刊名：Journal of Agricultural and Food Chemistry
- 出版年：2005
- 出版时间：February 9, 2005
- 年：2005
- 卷：53
- 期：3
- 页码：608 - 613
- 全文大小：80K
- 年卷期：v.53,no.3(February 9, 2005)
- ISSN：1520-5118
文摘
This is the first report for secondary metabolites in an African medicinal plant, Pachyelasma tessmannii(Leguminosae). Four novel saponins, pachyelasides A-D, were isolated from the methanol extractof the root bark by using recycling HPLC. These compounds showed molluscicidal activity (LD50 
8.0 
g/mL) against the South American snail, Biomphalaria glabratus. The structures were determinedon the basis of extensive nuclear magnetic resonance spectroscopic and matrix-assisted laserdesorption/ionization time-of-flight mass spectrometric studies.Keywords: Saponin; pachyelaside; Pachyelasma tessmannii; Leguminosae; molluscicide; Biomphalariaglabratus
8.0 g/mL) against the South American snail, Biomphalaria glabratus. The structures were determinedon the basis of extensive nuclear magnetic resonance spectroscopic and matrix-assisted laserdesorption/ionization time-of-flight mass spectrometric studies.Keywords: Saponin; pachyelaside; Pachyelasma tessmannii; Leguminosae; molluscicide; Biomphalariaglabratus