One-Pot Cascade Approach to Phenanthridine-Fused Quinazoliniminiums from Heteroenyne-Allenes

详细信息    查看全文

• 作者：Olajide E. Alawode ; Vijaya Kumar Naganaboina ; Thakshila Liyanage ; John Desper ; Sundeep Rayat
• 刊名：Organic Letters
• 出版年：2014
• 出版时间：March 7, 2014
• 年：2014
• 卷：16
• 期：5
• 页码：1494-1497
• 全文大小：274K
• 年卷期：v.16,no.5(March 7, 2014)
• ISSN：1523-7052

文摘

A one-pot cascade method to obtain functionalized phenanthridine-fused quinazoliniminiums from a variety of heteroenyne-allenes is described. This protocol involves formation of C鈥揘 and C鈥揅 bonds in a single step in the presence of a Lewis acid and trace water to afford pentacyclic title compounds in moderate to good yields.