Resistant Starch and Pullulan Reduce Postprandial Glucose, Insulin, and GLP-1, but Have No Effect on Satiety in Healthy Humans
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- 作者：Abby S. Klosterbuer ; William Thomas ; Joanne L. Slavin
- 刊名：Journal of Agricultural and Food Chemistry
- 出版年：2012
- 出版时间：December 5, 2012
- 年：2012
- 卷：60
- 期：48
- 页码：11928-11934
- 全文大小：376K
- 年卷期：v.60,no.48(December 5, 2012)
- ISSN：1520-5118
文摘
The aim of this study was to determine the effects of three novel fibers on satiety and serum parameters. In a randomized, double-blind, crossover design, fasted subjects (n = 20) consumed a low-fiber control breakfast or one of four breakfasts containing 25 g of fiber from soluble corn fiber (SCF) or resistant starch (RS), alone or in combination with pullulan (SCF+P and RS+P). Visual analog scales assessed appetite, and blood samples were collected to measure glucose, insulin, ghrelin, and glucagon-like peptide-1 (GLP-1). The fiber treatments did not influence satiety or energy intake compared to control. RS+P significantly reduced glucose, insulin, and GLP-1, but neither SCF treatment differed from control. To conclude, these fibers have little impact on satiety when provided as a mixed meal matched for calories and macronutrients. Additional research regarding the physiological effects of these novel fibers is needed to guide their use as functional ingredients in food products.