Switching the Cleavage Sites in Palladium on Carbon-Catalyzed Carbon–Carbon Bond Disconnection

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• 作者：Tomohiro Hattori ; Ryoya Takakura ; Tomohiro Ichikawa ; Yoshinari Sawama ; Yasunari Monguchi ; Hironao Sajiki
• 刊名：Journal of Organic Chemistry
• 出版年：2016
• 出版时间：April 1, 2016
• 年：2016
• 卷：81
• 期：7
• 页码：2737-2743
• 全文大小：441K
• ISSN：1520-6904

文摘

We have demonstrated a palladium on carbon-catalyzed approach to regioselectively alter the cleavage sites of the C–C bonds of cinnamaldehyde derivatives by a slight change in the reaction conditions in isopropanol under an O₂ atmosphere. Styrene derivatives could be selectively formed by the addition of Na₂CO₃ in association with the dissociation of carbon monoxide, while benzaldehyde derivatives were generated by the addition of CuCl and morpholine instead of Na₂CO₃.