Measuring the Length Distribution of Self-Assembled Lipid Nanotubes by Orientation Control with a High-Frequency Alternating Current Electric Field in Aqueous Solutions

详细信息    查看全文

• 作者：Ken Hirano*^† ; ; Masaru Aoyagi^‡ ; ; Tomomi Ishido^† ; ; Toshihiko Ooie^† ; ; Hiroshi Frusawa^§ ; ; Masumi Asakawa^‡ ; ; T
• 刊名：Analytical Chemistry
• 出版年：2009
• 出版时间：February 15, 2009
• 年：2009
• 卷：81
• 期：4
• 页码：1459-1464
• 全文大小：253K
• 年卷期：v.81,no.4(February 15, 2009)
• ISSN：1520-6882

文摘

The present work addresses the length distribution of self-assembled lipid nanotubes (LNTs) by controlling the orientation of the LNTs using an alternating current (ac) electric field in aqueous solutions. The effect of the ac field on the orientation and rotation of individual LNTs was examined to evaluate the optimum orientation frequency by visualizing the individual LNTs in real time. By using the high-frequency ac field, we have successfully measured the length distribution for two different types of LNTs and have quantitatively analyzed the maximum occurrences of the length distribution as well as the extension of the longer length region.