Supramolecular Signatures of Adenine-Containing Organostannoxane Assemblies

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• 作者：Vadapalli Chandrasekhar ; Subrata Kundu ; Jitendra Kumar ; Sandeep Verma ; Kandasamy Gopal ; Amaresh Chaturbedi ; Kuppuswamy Subramaniam
• 刊名：Crystal Growth & Design
• 出版年：2013
• 出版时间：April 3, 2013
• 年：2013
• 卷：13
• 期：4
• 页码：1665-1675
• 全文大小：745K
• 年卷期：v.13,no.4(April 3, 2013)
• ISSN：1528-7505

文摘

The reactions of 3-(N9-adeninyl) propanoic acid (LH) with various di- and triorganotin oxides have been investigated. Thus, the reaction of di-tert-butyltin oxide (t-Bu₂SnO)₃ in a 3:1 ratio afforded the dinuclear derivative [t-Bu₂Sn(渭-OH)L]₂路7H₂O (1). A similar reaction involving bis(tri-n-butyltin)oxide, (n-Bu₃Sn)₂O, in a 2:1 ratio afforded the one-dimensional (1D) coordination polymer [n-Bu₃SnL路0.33H₂O]_n (2). Similarly the reaction with (n-Bu₂SnO)_n in a 2:1 ratio afforded the tetranuclear [{n-Bu₂Sn}₂(渭₃-O)(渭-OH)L]₂ (3). On the other hand, a similar reaction in a 1:1 ratio also gave the tetranuclear product [{n-Bu₂Sn}₂(渭₃-O)L₂]₂ (4). The molecular structure of 1reveals a central dinuclear Sn₂O₂ motif where the two tin centers are bridged by two 渭-OH groups. Each tin is bound with a monodentate carboxylate group; the C鈺怬 unit of these carboxylates is involved in an intramolecular hydrogen bonding with the bridging OH unit. The supramolecular structure of 1 reveals the formation of a 1D zigzag chain mediated by intermolecular hydrogen bonding interaction through the Watson-Crick or the Hoogsteen faces. 2 is a 1D coordination polymer formed by the successive bridging of triorganotin units by the carboxylate ligand L. The supramolecular structure of 2 reveals that two 1D coordination polymers interact to generate novel adenine homotrimers formed as a result of alternating Watson-Crick鈥揥atson-Crick and Hoogsteen鈥揥atson-Crick interactions. The molecular structures of 3 and 4 reveal them to be tetranuclear possessing a ladder-like structure. The essential difference between their molecular structures is that in 4 there are four carboxylate ligands, while in 3 there are only two. Both of these complexes reveal intramolecular and intermolecular hydrogen bonding and 蟺路路路蟺 stacking interactions. The nematicidal activity of 1鈥?b>3 was examined against Caenorhabditis elegans. Compound 2 was found to be highly active, effecting a high mortality even at very low concentrations such as 25 or 10 ppm.