Palladium-Catalyzed Conjugate Addition of Terminal Alkynes to Enones

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• 作者：Lara Villarino ; Rebeca Garc铆a-Fandi帽o ; Fernando L贸pez ; Jos茅 L. Mascare帽as
• 刊名：Organic Letters
• 出版年：2012
• 出版时间：June 15, 2012
• 年：2012
• 卷：14
• 期：12
• 页码：2996-2999
• 全文大小：292K
• 年卷期：v.14,no.12(June 15, 2012)
• ISSN：1523-7052

文摘

A practical protocol for the hydroalkynylation of enones using Pd catalysis is reported. The reaction proceeds efficiently with a variety of alkynes as well as with several cyclic and acyclic enones, providing synthetically relevant 尾-alkynyl ketones in good to excellent yields.