Vicarious Nucleophilic Substitution of 伪-Hydrogen of BODIPY and Its Extension to Direct Ethenylation

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• 作者：Volker Leen ; Mark Van der Auweraer ; Noe虉l Boens ; Wim Dehaen
• 刊名：Organic Letters
• 出版年：2011
• 出版时间：March 18, 2011
• 年：2011
• 卷：13
• 期：6
• 页码：1470-1473
• 全文大小：734K
• 年卷期：v.13,no.6(March 18, 2011)
• ISSN：1523-7052

文摘

Direct, oxidizer-free substitution of the 3-hydrogen of BODIPY derivatives has been established through a vicarious nucleophilic substitution procedure. This methodology has been combined with a reversible Michael addition on nitrostyrenes to provide a novel, highly efficient entry to the valuable 3-styrylated BODIPY dyes.