Synthesis, Coordination Behavior, and Use in Asymmetric Hydrogenations of Walphos-Type Ligands

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• 作者：Yaping Wang ; Thomas Sturm ; Marianne Steurer ; Vladimir B. Arion ; Kurt Mereiter ; Felix Spindler ; Walter Weissensteiner
• 刊名：Organometallics
• 出版年：2008
• 出版时间：March 24, 2008
• 年：2008
• 卷：27
• 期：6
• 页码：1119 - 1127
• 全文大小：778K
• 年卷期：v.27,no.6(March 24, 2008)
• ISSN：1520-6041

文摘

A total of nine Walphos-type diphosphine ligands, all of which have a ferrocenyl-aryl backbone, have been synthesized, characterized, and tested in asymmetric ruthenium-, rhodium-, and iridium-catalyzed hydrogenations of alkenes, ketones, and one imine. Ruthenium- and rhodium-mediated hydrogenations of alkenes and ketones gave enantioselectivities of up to 95% and 97% ee, respectively. Ligand tuning was attempted by variation of the phosphorus-bound aryl and alkyl substituents and by attaching electron-donating or electron-withdrawing substituents to the backbone phenyl ring. Dichloropalladium(II) complexes of five ligands were synthesized, and in four cases the molecular structures were studied in solution as well as in the solid state.