Synthesis and Characterization of Circular Structures of i-Motif Tagged with Fluoresceins

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• 作者：Tianyan Zhou ; Xinming Li ; Magdeline Tao Tao Ng ; Yifan Wang ; Ngee Mien Quek ; Ji Luo ; Weixing Yuan ; Choon-Hong Tan ; Huaqiang Zeng ; Tianhu Li
• 刊名：Bioconjugate Chemistry
• 出版年：2009
• 出版时间：April 15, 2009
• 年：2009
• 卷：20
• 期：4
• 页码：644-647
• 全文大小：149K
• 年卷期：v.20,no.4(April 15, 2009)
• ISSN：1520-4812

文摘

Synthesis of a fluorescein-tagged circular structure of i-motif was accomplished during our investigations. The backbone circularity of this molecular probe and the presence of the fluorescent moiety within its structure were also confirmed through exonuclease hydrolysis and fluorescence spectroscopy.