Sonication鈥揗icrofluidics for Fabrication of Nanoparticle-Stabilized Microbubbles

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• 作者：Haosheng Chen ; Jiang Li ; Weizheng Zhou ; Eddie G. Pelan ; Simeon D. Stoyanov ; Luben N. Arnaudov ; Howard A. Stone
• 刊名：Langmuir
• 出版年：2014
• 出版时间：April 22, 2014
• 年：2014
• 卷：30
• 期：15
• 页码：4262-4266
• 全文大小：309K
• 年卷期：v.30,no.15(April 22, 2014)
• ISSN：1520-5827

文摘

An approach based upon sonication鈥搈icrofluidics is presented to fabricate nanoparticle-coated microbubbles. The gas-in-liquid slug flow formed in a microchannel is subjected to ultrasound, leading to cavitation at the gas鈥搇iquid interface. Therefore, microbubbles are formed and then stabilized by the nanoparticles contained in the liquid. Compared to the conventional sonication method, this sonication鈥搈icrofluidics continuous flow approach has unlimited gas nuclei for cavitation that yields continuous production of foam with shorter residence time. By controlling the flow rate ratios of the gas to the liquid, this method also achieves a higher production volume, smaller bubble size, and less waste of the nanoparticles needed to stabilize the microbubbles.