Enantioselective Total Synthesis of the Mexicanolides: Khayasin, Proceranolide, and Mexicanolide

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• 作者：Jonathan M. Faber ; Wilhelm A. Eger ; Craig M. Williams
• 刊名：The Journal of Organic Chemistry
• 出版年：2012
• 出版时间：October 19, 2012
• 年：2012
• 卷：77
• 期：20
• 页码：8913-8921
• 全文大小：436K
• 年卷期：v.77,no.20(October 19, 2012)
• ISSN：1520-6904

文摘

The enantioselective total synthesis of the limonoids khayasin, proceranolide and mexicanolide was achieved via a convergent strategy utilizing a tactic aimed at incorporating natural products as advanced intermediates. This extended biomimetically inspired approach additionally achieved the enantioselective total synthesis of the intermediates azedaralide and cipadonoid B.