Pd(II)-Catalyzed C3-Selective Arylation of Pyridine with (Hetero)arenes

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• 作者：Guo-Lin Gao ; Wujiong Xia ; Pankaj Jain ; Jin-Quan Yu
• 刊名：Organic Letters
• 出版年：2016
• 出版时间：February 19, 2016
• 年：2016
• 卷：18
• 期：4
• 页码：744-747
• 全文大小：339K
• ISSN：1523-7052

文摘

Palladium catalyzed, nondirected C3-selective arylation of pyridines with arenes and heteroarenes in the presence of 1,10-phenanthroline as the ligand has been developed. The optimized conditions allow for a highly C3-selective arylation of pyridines, affording various 3,3′-bipyridines and 3-arylpyridines.